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Tuning of conformational preorganization in model 2′,5′- and 3′,5′-linked oligonucleotides by 3′- and 2′-O-methoxyethyl modification
Conformational properties of trimeric and tetrameric 2′,5′-linked oligonucleotides, 3′-MOE-A(3)(2′,5′) (1) and 3′-MOE-A(4)(2′,5′) (2), and their 3′,5′-linked analogs, 2′-MOE-A(3)(3′,5′) (3) and 2′-MOE-A(4)(3′,5′) (4), were examined with the use of heteronuclear NMR spectroscopy. The temperature-depe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153733/ https://ncbi.nlm.nih.gov/pubmed/12682357 |
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