Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

Neuronal cultures in vitro readily oxidized both D-[(14)C]glucose and l-[(14)C]lactate to (14)CO(2), whereas astroglial cultures oxidized both substrates sparingly and metabolized glucose predominantly to lactate and released it into the medium. [(14)C]Glucose oxidation to (14)CO(2) varied inversely...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Itoh, Yoshiaki, Esaki, Takanori, Shimoji, Kazuaki, Cook, Michelle, Law, Mona J., Kaufman, Elaine, Sokoloff, Louis
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC153649/
https://ncbi.nlm.nih.gov/pubmed/12668764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0831078100
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires