The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans

Sex specificity of neural mechanisms modulating nociceptive information has been demonstrated in rodents, and these qualitative sex differences appear to be relevant to analgesia from κ-opioid receptor agonists, a drug class reported to be clinically effective only in women. Via quantitative trait l...

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Main Authors: Mogil, Jeffrey S., Wilson, Sonya G., Chesler, Elissa J., Rankin, Andrew L., Nemmani, Kumar V. S., Lariviere, William R., Groce, M. Kristina, Wallace, Margaret R., Kaplan, Lee, Staud, Roland, Ness, Timothy J., Glover, Toni L., Stankova, Magda, Mayorov, Alexander, Hruby, Victor J., Grisel, Judith E., Fillingim, Roger B.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153647/
https://ncbi.nlm.nih.gov/pubmed/12663858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730053100
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