Hda-mediated inactivation of the DnaA protein and dnaA gene autoregulation act in concert to ensure homeostatic maintenance of the Escherichia coli chromosome

Initiation of DNA replication in Eschericia coli requires the ATP-bound form of the DnaA protein. The conversion of DnaA–ATP to DnaA–ADP is facilitated by a complex of DnaA, Hda (homologous to DnaA), and DNA-loaded β-clamp proteins in a process termed RIDA (regulatory inactivation of DnaA). Hda-defi...

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Detalhes bibliográficos
Main Authors: Riber, Leise, Olsson, Jan A., Jensen, Rasmus B., Skovgaard, Ole, Dasgupta, Santanu, Marinus, Martin G., Løbner-Olesen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536062/
https://ncbi.nlm.nih.gov/pubmed/16882985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.379506
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