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Hda-mediated inactivation of the DnaA protein and dnaA gene autoregulation act in concert to ensure homeostatic maintenance of the Escherichia coli chromosome

Initiation of DNA replication in Eschericia coli requires the ATP-bound form of the DnaA protein. The conversion of DnaA–ATP to DnaA–ADP is facilitated by a complex of DnaA, Hda (homologous to DnaA), and DNA-loaded β-clamp proteins in a process termed RIDA (regulatory inactivation of DnaA). Hda-defi...

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Bibliografische gegevens
Hoofdauteurs: Riber, Leise, Olsson, Jan A., Jensen, Rasmus B., Skovgaard, Ole, Dasgupta, Santanu, Marinus, Martin G., Løbner-Olesen, Anders
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1536062/
https://ncbi.nlm.nih.gov/pubmed/16882985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.379506
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