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Interfering with TGFβ-induced Smad3 nuclear accumulation differentially affects TGFβ-dependent gene expression
BACKGROUND: Transforming growth factor-β (TGFβ) plays an important role in late-stage carcinogenesis by stimulating invasive behavior of cancer cells, promoting neo-angiogenesis and by helping cancer cells to escape surveillance by the immune system. It also supports colonization of the bone by meta...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153548/ https://ncbi.nlm.nih.gov/pubmed/12747808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-2-20 |
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