Mature helper T cell requirement for immunoglobulin production by neonatal native B cells injected intraperitoneally into severe combined immunodeficient (SCID) mice.

It is accepted that human neonatal naive B cells produce mainly IgM in vivo as well as in vitro. Our previous work has demonstrated that i.p. injection of neonatal B cells together with adult mature T cells induces substantial levels of human IgG in the serum of SCID recipient mice. The present stud...

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Detalhes bibliográficos
Main Authors: Hasui, M, Miyawaki, T, Ichihara, T, Niida, Y, Iwai, K, Yachie, A, Seki, H, Taniguchi, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534912/
https://ncbi.nlm.nih.gov/pubmed/8306511
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