Delineation of producing ability of IgG and IgA subclasses by naive B cells in newborn infants and adult individuals.

Neonatal B cells with the naive (sIgD+) phenotype are able to generate IgG- and IgA-producing cells as well as IgM production in the presence of memory CD4+ T cells expressing L-selectin (CD62L) in pokeweed mitogen-stimulated cultures. We used this system to examine comparatively the ability of naiv...

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Main Authors: Yachie, A, Konno, A, Ohta, K, Wada, T, Seki, H, Taniguchi, N, Miyawaki, T
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553323/
https://ncbi.nlm.nih.gov/pubmed/7554391
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