Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: Indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17

Bruck syndrome is characterized by the presence of osteoporosis, joint contractures, fragile bones, and short stature. We report that lysine residues within the telopeptides of collagen type I in bone are underhydroxylated, leading to aberrant crosslinking, but that the lysine residues in the triple...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bank, Ruud A., Robins, Simon P., Wijmenga, Cisca, Breslau-Siderius, Liesbeth J., Bardoel, Alfons F. J., Van der Sluijs, Hans A., Pruijs, Hans E. H., TeKoppele, Johan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC15349/
https://ncbi.nlm.nih.gov/pubmed/9927692
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky