Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: Indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17

Bruck syndrome is characterized by the presence of osteoporosis, joint contractures, fragile bones, and short stature. We report that lysine residues within the telopeptides of collagen type I in bone are underhydroxylated, leading to aberrant crosslinking, but that the lysine residues in the triple...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	Proc Natl Acad Sci U S A
Үндсэн зохиолчид:	Bank, Ruud A., Robins, Simon P., Wijmenga, Cisca, Breslau-Siderius, Liesbeth J., Bardoel, Alfons F. J., Van der Sluijs, Hans A., Pruijs, Hans E. H., TeKoppele, Johan M.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	National Academy of Sciences 1999
Нөхцлүүд:	Biological Sciences
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.1054
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!