Combined effects of FK506 (tacrolimus) and cyclophosphamide on atypical B220+ T cells, cytokine gene expression and disease activity in MRL/MpJ-lpr/lpr mice.

Groups of female MRL/MpJ-lpr/lpr mice received either saline or FK506 (tacrolimus; 2 mg/kg intraperitoneally) three times weekly, cyclophosphamide (CY; 20 mg/kg) once monthly, or both drugs from 8 weeks of age. Median survival for untreated and CY-treated mice was 26 weeks, and for FK506- and FK506...

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Detaylı Bibliyografya
Asıl Yazarlar: Woo, J, Wright, T M, Lemster, B, Borochovitz, D, Nalesnik, M A, Thomson, A W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534278/
https://ncbi.nlm.nih.gov/pubmed/7535208
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