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Family-Based versus Unrelated Case-Control Designs for Genetic Associations
The most simple and commonly used approach for genetic associations is the case-control study design of unrelated people. This design is susceptible to population stratification. This problem is obviated in family-based studies, but it is usually difficult to accumulate large enough samples of well-...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1534078/ https://ncbi.nlm.nih.gov/pubmed/16895437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020123 |
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