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Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

Hepatic insulin resistance affects both carbohydrate and lipid metabolism. It has been proposed that insulin controls these 2 metabolic branches through distinct signaling pathways. FoxO transcription factors are considered effectors of the pathway regulating hepatic glucose production. Here we show...

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Détails bibliographiques
Auteurs principaux: Matsumoto, Michihiro, Han, Seongah, Kitamura, Tadahiro, Accili, Domenico
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533874/
https://ncbi.nlm.nih.gov/pubmed/16906224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27047
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