Inability of a Fusion Protein of IL-2 and Diphtheria Toxin (Denileukin Diftitox, DAB(389)IL-2, ONTAK) to Eliminate Regulatory T Lymphocytes in Patients With Melanoma

Elimination of regulatory T lymphocytes may provide a way to break self-tolerance and unleash the anti-tumor properties of circulating lymphocytes. The use of fusion proteins, which link cytotoxic molecules to receptor targets, provides one approach to this problem. This study examined the ability o...

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Xehetasun bibliografikoak
Egile Nagusiak: Attia, Peter, Maker, Ajay V., Haworth, Leah R., Rogers-Freezer, Linda, Rosenberg, Steven A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533764/
https://ncbi.nlm.nih.gov/pubmed/16224276
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