Prevention of Human Rhinovirus Infection by Multivalent Fab Molecules Directed against ICAM-1

We have developed a technology for improving avidity by making bivalent, trivalent, or tetravalent recombinant polypeptides. We designed tripartite proteins consisting of the Fab fragment of an antibody fused with a hinge derived from human immunoglobulin D that was further linked to polymerization...

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Detalhes bibliográficos
Main Authors: Charles, Catherine H., Luo, Guang X., Kohlstaedt, Lori A., Morantte, Ianessa G., Gorfain, Elliott, Cao, Linguang, Williams, Jimmy H., Fang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153330/
https://ncbi.nlm.nih.gov/pubmed/12709314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1503-1508.2003
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