Fungicidal Synergism of Fluconazole and Cyclosporine in Candida albicans Is Not Dependent on Multidrug Efflux Transporters Encoded by the CDR1, CDR2, CaMDR1, and FLU1 Genes

The combination of fluconazole (FLC) and cyclosporine (CY) is fungicidal in FLC-susceptible C. albicans (O. Marchetti, P. Moreillon, M. P. Glauser, J. Bille, and D. Sanglard, Antimicrob. Agents Chemother. 44:2373-2381, 2000). The mechanism of this synergism is unknown. CY has several cellular target...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Marchetti, Oscar, Moreillon, Philippe, Entenza, Josè M., Vouillamoz, Jacques, Glauser, Michel P., Bille, Jacques, Sanglard, Dominique
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12709323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.5.1565-1570.2003
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