Fungicidal Synergism of Fluconazole and Cyclosporine in Candida albicans Is Not Dependent on Multidrug Efflux Transporters Encoded by the CDR1, CDR2, CaMDR1, and FLU1 Genes

The combination of fluconazole (FLC) and cyclosporine (CY) is fungicidal in FLC-susceptible C. albicans (O. Marchetti, P. Moreillon, M. P. Glauser, J. Bille, and D. Sanglard, Antimicrob. Agents Chemother. 44:2373-2381, 2000). The mechanism of this synergism is unknown. CY has several cellular target...

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Dettagli Bibliografici
Autori principali: Marchetti, Oscar, Moreillon, Philippe, Entenza, Josè M., Vouillamoz, Jacques, Glauser, Michel P., Bille, Jacques, Sanglard, Dominique
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC153326/
https://ncbi.nlm.nih.gov/pubmed/12709323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1565-1570.2003
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