Sensitive Bioassay for Determination of Fluconazole Concentrations in Plasma Using a Candida albicans Mutant Hypersusceptible to Azoles

The antifungal agent fluconazole (FLC) is widely used in clinical practice. Monitoring FLC levels is useful in complicated clinical settings and in experimental infection models. A bioassay using Candida pseudotropicalis, a simple and cost-effective method, is validated only for FLC levels ranging f...

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Main Authors: Marchetti, Oscar, Majcherczyk, Paul A., Glauser, Michel P., Bille, Jacques, Moreillon, Philippe, Sanglard, Dominique
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90358/
https://ncbi.nlm.nih.gov/pubmed/11181345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.696-700.2001
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