Sensitive Bioassay for Determination of Fluconazole Concentrations in Plasma Using a Candida albicans Mutant Hypersusceptible to Azoles

The antifungal agent fluconazole (FLC) is widely used in clinical practice. Monitoring FLC levels is useful in complicated clinical settings and in experimental infection models. A bioassay using Candida pseudotropicalis, a simple and cost-effective method, is validated only for FLC levels ranging f...

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Detalhes bibliográficos
Main Authors: Marchetti, Oscar, Majcherczyk, Paul A., Glauser, Michel P., Bille, Jacques, Moreillon, Philippe, Sanglard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90358/
https://ncbi.nlm.nih.gov/pubmed/11181345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.696-700.2001
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