Fungicidal Synergism of Fluconazole and Cyclosporine in Candida albicans Is Not Dependent on Multidrug Efflux Transporters Encoded by the CDR1, CDR2, CaMDR1, and FLU1 Genes

The combination of fluconazole (FLC) and cyclosporine (CY) is fungicidal in FLC-susceptible C. albicans (O. Marchetti, P. Moreillon, M. P. Glauser, J. Bille, and D. Sanglard, Antimicrob. Agents Chemother. 44:2373-2381, 2000). The mechanism of this synergism is unknown. CY has several cellular target...

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Détails bibliographiques
Auteurs principaux: Marchetti, Oscar, Moreillon, Philippe, Entenza, Josè M., Vouillamoz, Jacques, Glauser, Michel P., Bille, Jacques, Sanglard, Dominique
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC153326/
https://ncbi.nlm.nih.gov/pubmed/12709323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1565-1570.2003
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