Fungicidal Synergism of Fluconazole and Cyclosporine in Candida albicans Is Not Dependent on Multidrug Efflux Transporters Encoded by the CDR1, CDR2, CaMDR1, and FLU1 Genes

The combination of fluconazole (FLC) and cyclosporine (CY) is fungicidal in FLC-susceptible C. albicans (O. Marchetti, P. Moreillon, M. P. Glauser, J. Bille, and D. Sanglard, Antimicrob. Agents Chemother. 44:2373-2381, 2000). The mechanism of this synergism is unknown. CY has several cellular target...

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Bibliographic Details
Main Authors: Marchetti, Oscar, Moreillon, Philippe, Entenza, Josè M., Vouillamoz, Jacques, Glauser, Michel P., Bille, Jacques, Sanglard, Dominique
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC153326/
https://ncbi.nlm.nih.gov/pubmed/12709323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1565-1570.2003
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