Fungicidal Synergism of Fluconazole and Cyclosporine in Candida albicans Is Not Dependent on Multidrug Efflux Transporters Encoded by the CDR1, CDR2, CaMDR1, and FLU1 Genes

The combination of fluconazole (FLC) and cyclosporine (CY) is fungicidal in FLC-susceptible C. albicans (O. Marchetti, P. Moreillon, M. P. Glauser, J. Bille, and D. Sanglard, Antimicrob. Agents Chemother. 44:2373-2381, 2000). The mechanism of this synergism is unknown. CY has several cellular target...

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Detalhes bibliográficos
Main Authors: Marchetti, Oscar, Moreillon, Philippe, Entenza, Josè M., Vouillamoz, Jacques, Glauser, Michel P., Bille, Jacques, Sanglard, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153326/
https://ncbi.nlm.nih.gov/pubmed/12709323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1565-1570.2003
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