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Pharmacodynamics of a Novel Des-F(6)-Quinolone, BMS-284756, against Streptococcus pneumoniae in the Thigh Infection Model

BMS-284756 is a novel quinolone that lacks the six-position fluorine typical of existing compounds. Despite this structural change, BMS-284756 maintains potent antibacterial activity against gram-negative and gram-positive aerobic and anaerobic pathogens. The objective of this study was to define th...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Nicolau, David P., Mattoes, Holly M., Banevicius, Maryanne, Xuan, Dawei, Nightingale, Charles H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12709332/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.5.1630-1635.2003
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