Histidine and Aspartic Acid Residues Important for Immunoglobulin G Endopeptidase Activity of the Group A Streptococcus Opsonophagocytosis-Inhibiting Mac Protein

The secreted Mac protein made by serotype M1 group A Streptococcus (GAS) (designated Mac(5005)) inhibits opsonophagocytosis and killing of GAS by human polymorphonuclear neutrophils. This protein also has cysteine endopeptidase activity against human immunoglobulin G (IgG). Site-directed mutagenesis...

Celý popis

Podrobná bibliografie

Vydáno v:	Infect Immun
Hlavní autoři:	Lei, Benfang, Liu, Mengyao, Meyers, Elishia G., Manning, Heather M., Nagiec, Michael J., Musser, James M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Molecular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.5.2881-2884.2003
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!