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Determinants within an 18-Amino-Acid U1A Autoregulatory Domain That Uncouple Cooperative RNA Binding, Inhibition of Polyadenylation, and Homodimerization

The human U1 snRNP-specific U1A protein autoregulates its own production by binding to and inhibiting the polyadenylation of its own pre-mRNA. Previous work demonstrated that a short sequence of U1A protein is essential for autoregulation and contains three distinct activities, which are (i) coopera...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Cell Biol
Principais autores: Guan, Fei, Palacios, Daphne, Hussein, Reem I., Gunderson, Samuel I.
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3163-3172.2003
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