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U1 snRNP-Dependent Suppression of Polyadenylation: Physiological Role and Therapeutic Opportunities in Cancer

Pre-mRNA splicing and polyadenylation are critical steps in the maturation of eukaryotic mRNA. U1 snRNP is an essential component of the splicing machinery and participates in splice-site selection and spliceosome assembly by base-pairing to the 5′ splice site. U1 snRNP also plays an additional, non...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Lee Spraggon, Luca Cartegni
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Wiley 2013-01-01
Цуврал:International Journal of Cell Biology
Онлайн хандалт:http://dx.doi.org/10.1155/2013/846510
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