Long CTG Tracts from the Myotonic Dystrophy Gene Induce Deletions and Rearrangements during Recombination at the APRT Locus in CHO Cells

Expansion of CTG triplet repeats in the 3′ untranslated region of the DMPK gene causes the autosomal dominant disorder myotonic dystrophy. Instability of CTG repeats is thought to arise from their capacity to form hairpin DNA structures. How these structures interact with various aspects of DNA meta...

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書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Meservy, James L., Sargent, R. Geoffrey, Iyer, Ravi R., Chan, Fung, McKenzie, Gregory J., Wells, Robert D., Wilson, John H.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2003
主題:	DNA Dynamics and Chromosome Structure
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3152-3162.2003
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