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Regulation of the Bone-Specific Osteocalcin Gene by p300 Requires Runx2/Cbfa1 and the Vitamin D3 Receptor but Not p300 Intrinsic Histone Acetyltransferase Activity

p300 is a multifunctional transcriptional coactivator that serves as an adapter for several transcription factors including nuclear steroid hormone receptors. p300 possesses an intrinsic histone acetyltransferase (HAT) activity that may be critical for promoting steroid-dependent transcriptional act...

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Udgivet i:Mol Cell Biol
Principais autores: Sierra, Jose, Villagra, Alejandro, Paredes, Roberto, Cruzat, Fernando, Gutierrez, Soraya, Javed, Amjad, Arriagada, Gloria, Olate, Juan, Imschenetzky, Maria, van Wijnen, Andre J., Lian, Jane B., Stein, Gary S., Stein, Janet L., Montecino, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153185/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3339-3351.2003
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