Maintenance of Open Chromatin and Selective Genomic Occupancy at the Cell Cycle-Regulated Histone H4 Promoter during Differentiation of HL-60 Promyelocytic Leukemia Cells

During the shutdown of proliferation and onset of differentiation of HL-60 promyelocytic leukemia cells, expression of the cell cycle-dependent histone genes is downregulated at the level of transcription. To address the mechanism by which this regulation occurs, we examined the chromatin structure...

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Detalhes bibliográficos
Main Authors: Hovhannisyan, Hayk, Cho, Brian, Mitra, Partha, Montecino, Martin, Stein, Gary S., van Wijnen, Andre J., Stein, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141140/
https://ncbi.nlm.nih.gov/pubmed/12556504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1460-1469.2003
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