Microarray and Biochemical Analysis of Lovastatin-Induced Apoptosis of Squamous Cell Carcinomas

We recently identified 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme of the mevalonate pathway, as a potential therapeutic target of the head and neck squamous cell carcinomas (HNSCC) and cervical carcinomas (CC). The products of this complex biochemical pathway...

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Detalhes bibliográficos
Main Authors: Dimitroulakos, Jim, Marhin, Wilson H, Tokunaga, Jason, Irish, Jonathan, Gullane, Patrick, Penn, Linda Z, Kamel-Reid, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531704/
https://ncbi.nlm.nih.gov/pubmed/12082550
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