Expression of the Platelet-Derived Growth Factor Receptor in Prostate Cancer and Treatment Implications with Tyrosine Kinase Inhibitors

The platelet-derived growth factor receptor (PDGFR) is a receptor tyrosine kinase overexpressed in a subset of solid tumors and therefore is the target of drugs inhibiting this function such as imatinib mesylate (Gleevec). Thus far, drug therapy has played a limited role in the treatment of localize...

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Bibliographic Details
Main Authors: Hofer, Matthias D, Fecko, Alice, Shen, Ronglai, Setlur, Sunita R, Pienta, Kenneth G, Tomlins, Scott A, Chinnaiyan, Arul M, Rubin, Mark A
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2004
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531653/
https://ncbi.nlm.nih.gov/pubmed/15548358
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