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Expression of the Platelet-Derived Growth Factor Receptor in Prostate Cancer and Treatment Implications with Tyrosine Kinase Inhibitors

The platelet-derived growth factor receptor (PDGFR) is a receptor tyrosine kinase overexpressed in a subset of solid tumors and therefore is the target of drugs inhibiting this function such as imatinib mesylate (Gleevec). Thus far, drug therapy has played a limited role in the treatment of localize...

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Detalhes bibliográficos
Main Authors: Hofer, Matthias D, Fecko, Alice, Shen, Ronglai, Setlur, Sunita R, Pienta, Kenneth G, Tomlins, Scott A, Chinnaiyan, Arul M, Rubin, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531653/
https://ncbi.nlm.nih.gov/pubmed/15548358
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