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Characterization of TMPRSS2-ETS Gene Aberrations in Androgen Independent Metastatic Prostate Cancer

Recurrent gene fusions between the androgen-regulated gene TMPRSS2 and the ETS transcription factor family members ERG, ETV1, and ETV4 have been identified as a critical event in prostate cancer development. In this study, we characterized the prevalence and diversity of these rearrangements in horm...

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Detalhes bibliográficos
Main Authors: Mehra, Rohit, Tomlins, Scott A., Yu, Jianjun, Cao, Xuhong, Wang, Lei, Menon, Anjana, Pienta, Kenneth J., Shah, Rajal B., Chinnaiyan, Arul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677168/
https://ncbi.nlm.nih.gov/pubmed/18483239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6154
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