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Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis

Matrix metalloprotease type 9 (MMP-9) has been functionally implicated in VEGF activation, the induction and maintenance of chronic angiogenesis, and early stage tumor growth in a number of mouse models of cancer. In this article, we have identified two inflammatory cell types that are major sources...

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Bibliografiske detaljer
Main Authors: Nozawa, Hiroaki, Chiu, Christopher, Hanahan, Douglas
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531646/
https://ncbi.nlm.nih.gov/pubmed/16891410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601807103
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