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The Third P-loop Domain in Cytoplasmic Dynein Heavy Chain Is Essential for Dynein Motor Function and ATP-sensitive Microtubule Binding

Sequence comparisons and structural analyses show that the dynein heavy chain motor subunit is related to the AAA family of chaperone-like ATPases. The core structure of the dynein motor unit derives from the assembly of six AAA domains into a hexameric ring. In dynein, the first four AAA domains co...

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Hlavní autoři: Silvanovich, Andre, Li, Min-gang, Serr, Madeline, Mische, Sarah, Hays, Thomas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC153106/
https://ncbi.nlm.nih.gov/pubmed/12686593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-10-0675
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