NuMA recruits dynein activity to microtubule minus-ends at mitosis

To build the spindle at mitosis, motors exert spatially regulated forces on microtubules. We know that dynein pulls on mammalian spindle microtubule minus-ends, and this localized activity at ends is predicted to allow dynein to cluster microtubules into poles. How dynein becomes enriched at minus-e...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Christina L Hueschen, Samuel J Kenny, Ke Xu, Sophie Dumont
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2017-11-01
Цуврал:	eLife
Нөхцлүүд:	Potorous tridactylus mitosis spindle microtubule dynein minus-end
Онлайн хандалт:	https://elifesciences.org/articles/29328
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!