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Differential Induction of Nuclear Factor-κB and Activator Protein-1 Activity after CD40 Ligation Is Associated with Primary Human Hepatocyte Apoptosis or Intrahepatic Endothelial Cell Proliferation

CD40, a tumor necrosis factor receptor superfamily member, is up-regulated on intraheptatic endothelial cells (IHEC) and epithelial cells during inflammatory liver disease, and there is evidence that the functional outcome of CD40 ligation differs between cell types. Ligation of CD40 on cholangiocyt...

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Main Authors: Choudhury, Jalal Ahmed, Russell, Clare L., Randhawa, Satinder, Young, Lawrence S., Adams, David H., Afford, Simon C.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153104/
https://ncbi.nlm.nih.gov/pubmed/12686591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-07-0378
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