Loading...

CD40 Activation Induces Apoptosis in Cultured Human Hepatocytes via Induction of Cell Surface Fas Ligand Expression and Amplifies Fas-mediated Hepatocyte Death during Allograft Rejection

We propose that a novel mechanism of hepatocyte apoptosis, involving a cooperative interaction between CD40 and Fas, is involved in the hepatocyte loss of chronic liver allograft rejection. We detected increased hepatocyte expression of Fas, Fas ligand (FasL), and CD40 associated with dropout of cen...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Afford, Simon C., Randhawa, Satinder, Eliopoulos, Aristides G., Hubscher, Stefan G., Young, Lawrence S., Adams, David H.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192998/
https://ncbi.nlm.nih.gov/pubmed/9892626
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!