Fas/Fas Ligand Interaction in Human Colorectal Hepatic Metastases : A Mechanism of Hepatocyte Destruction to Facilitate Local Tumor Invasion

This study demonstrates a novel role for the Fas pathway in the promotion of local tumor growth by inducing apoptotic cell death in normal hepatocytes at the tumor margin in colorectal hepatic metastases. Our results show that >85% of lymphocytes infiltrating colorectal liver cancer express high...

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Detalhes bibliográficos
Principais autores: Yoong, Khong F., Afford, Simon C., Randhawa, Satinder, Hubscher, Stefan G., Adams, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866426/
https://ncbi.nlm.nih.gov/pubmed/10079247
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