Demonstration of functional coupling between γ-aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesicles

l-Glutamic acid decarboxylase (GAD) exists as both membrane-associated and soluble forms in the mammalian brain. Here, we propose that there is a functional and structural coupling between the synthesis of γ-aminobutyric acid (GABA) by membrane-associated GAD and its packaging into synaptic vesicles...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jin, Hong, Wu, Heng, Osterhaus, Gregory, Wei, Jianning, Davis, Kathleen, Sha, Di, Floor, Eric, Hsu, Che-Chang, Kopke, Richard D., Wu, Jang-Yen
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The National Academy of Sciences 2003
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC153086/
https://ncbi.nlm.nih.gov/pubmed/12634427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730698100
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