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Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain

By integrating convergent protein engineering and rational inhibitor design, we have developed an in vivo conditional protein knockout and/or manipulation technology. This method is based on the creation of a specific interaction interface between a modified protein domain and sensitized inhibitors....

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Wang, Huimin, Shimizu, Eiji, Tang, Ya-Ping, Cho, Min, Kyin, Maureen, Zuo, Wenqi, Robinson, Daphne A., Alaimo, Peter J., Zhang, Chao, Morimoto, Hiromi, Zhuo, Min, Feng, Ruiben, Shokat, Kevan M., Tsien, Joe Z.
פורמט: Artigo
שפה:Inglês
יצא לאור: The National Academy of Sciences 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC153085/
https://ncbi.nlm.nih.gov/pubmed/12646704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0636870100
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