Inducible protein knockout reveals temporal requirement of CaMKII reactivation for memory consolidation in the brain

By integrating convergent protein engineering and rational inhibitor design, we have developed an in vivo conditional protein knockout and/or manipulation technology. This method is based on the creation of a specific interaction interface between a modified protein domain and sensitized inhibitors....

詳細記述

保存先:
書誌詳細
主要な著者: Wang, Huimin, Shimizu, Eiji, Tang, Ya-Ping, Cho, Min, Kyin, Maureen, Zuo, Wenqi, Robinson, Daphne A., Alaimo, Peter J., Zhang, Chao, Morimoto, Hiromi, Zhuo, Min, Feng, Ruiben, Shokat, Kevan M., Tsien, Joe Z.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2003
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC153085/
https://ncbi.nlm.nih.gov/pubmed/12646704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0636870100
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