Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

The transcription factor signal transducer and activator of transcription 3 (Stat3) is constitutively activated in a variety of cancers including squamous cell carcinoma of the head and neck (SCCHN). Previous investigations have demonstrated that activated Stat3 contributes to a loss of growth contr...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Leong, Paul L., Andrews, Genevieve A., Johnson, Daniel E., Dyer, Kevin F., Xi, Sichuan, Mai, Jeffrey C., Robbins, Paul D., Gadiparthi, Seshu, Burke, Nancy A., Watkins, Simon F., Grandis, Jennifer Rubin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640143/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0534764100
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