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Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

The transcription factor signal transducer and activator of transcription 3 (Stat3) is constitutively activated in a variety of cancers including squamous cell carcinoma of the head and neck (SCCHN). Previous investigations have demonstrated that activated Stat3 contributes to a loss of growth contr...

Celý popis

Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Leong, Paul L., Andrews, Genevieve A., Johnson, Daniel E., Dyer, Kevin F., Xi, Sichuan, Mai, Jeffrey C., Robbins, Paul D., Gadiparthi, Seshu, Burke, Nancy A., Watkins, Simon F., Grandis, Jennifer Rubin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0534764100
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