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Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

The transcription factor signal transducer and activator of transcription 3 (Stat3) is constitutively activated in a variety of cancers including squamous cell carcinoma of the head and neck (SCCHN). Previous investigations have demonstrated that activated Stat3 contributes to a loss of growth contr...

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Kaydedildi:
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Leong, Paul L., Andrews, Genevieve A., Johnson, Daniel E., Dyer, Kevin F., Xi, Sichuan, Mai, Jeffrey C., Robbins, Paul D., Gadiparthi, Seshu, Burke, Nancy A., Watkins, Simon F., Grandis, Jennifer Rubin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12640143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0534764100
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