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How does cyanide inhibit superoxide reductase? Insight from synthetic Fe(III)N(4)S model complexes

Superoxide reductases (SORs) are nonheme iron-containing enzymes that reduce HO(2) to H(2)O(2). Exogenous substrates such as N [Formula: see text] and CN(−) have been shown to bind to the catalytic iron site of SOR, and cyanide acts as an inhibitor. To understand how these exogenous ligands alter th...

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Detalhes bibliográficos
Main Authors: Shearer, Jason, Fitch, Sarah B., Kaminsky, Werner, Benedict, Jason, Scarrow, Robert C., Kovacs, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152980/
https://ncbi.nlm.nih.gov/pubmed/12655068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0637029100
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