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Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-β ligand:receptor interactions

The TGF-β superfamily of ligands and receptors stimulate cellular events in diverse processes ranging from cell fate specification in development to immune suppression. Activins define a major subgroup of TGF-β ligands that regulate cellular differentiation, proliferation, activation and apoptosis....

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Detalhes bibliográficos
Main Authors: Thompson, Thomas B., Woodruff, Teresa K., Jardetzky, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152900/
https://ncbi.nlm.nih.gov/pubmed/12660162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg156
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