Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

We report that HMGN1, a nucleosome binding protein that destabilizes the higher-order chromatin structure, modulates the repair rate of ultraviolet light (UV)-induced DNA lesions in chromatin. Hmgn1(–/–) mouse embryonic fibroblasts (MEFs) are hypersensitive to UV, and the removal rate of photoproduc...

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Main Authors: Birger, Yehudit, West, Katherine L., Postnikov, Yuri V., Lim, Jae-Hwan, Furusawa, Takashi, Wagner, James P., Laufer, Craig S., Kraemer, Kenneth H., Bustin, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2003
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC152887/
https://ncbi.nlm.nih.gov/pubmed/12660172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg142
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