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Novel amplification of DNA in a hairpin structure: towards a radical elimination of PCR errors from amplified DNA

Errors introduced during PCR amplification set a selectivity limit for microsatellite analysis and molecular mutation detection methods since polymerase misincorporations invariably get confused with genuine mutations. Here we present hairpin-PCR, a new form of PCR that completely separates genuine...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Kaur, Manjit, Makrigiorgos, G. Mike
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12626725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng026
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