Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1)

The transcription factor STAT-1 (signal transducer and activator of transcription-1) plays a pivotal role in the expression of inflammatory gene products involved in the pathogenesis of arthritis such as various cytokines and the CD40/CD40 ligand (CD40/CD40L) receptor-ligand dyad. The therapeutic ef...

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Main Authors: Hückel, Marion, Schurigt, Uta, Wagner, Andreas H, Stöckigt, Renate, Petrow, Peter K, Thoss, Klaus, Gajda, Mieczyslaw, Henzgen, Steffen, Hecker, Markus, Bräuer, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526583/
https://ncbi.nlm.nih.gov/pubmed/16507120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1869
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