Partial protection against collagen antibody-induced arthritis in PARP-1 deficient mice

Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear DNA-binding protein that participates in the regulation of DNA repair and maintenance of genomic integrity. In addition, PARP-1 has a role in several models of inflammation disease, where its absence or inactivation confers protection. The aim of t...

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Bibliografiske detaljer
Main Authors: García, Samuel, Bodaño, Ana, González, Antonio, Forteza, Jerónimo, Gómez-Reino, Juan J, Conde, Carmen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1526570/
https://ncbi.nlm.nih.gov/pubmed/16356201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1865
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