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Partial protection against collagen antibody-induced arthritis in PARP-1 deficient mice
Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear DNA-binding protein that participates in the regulation of DNA repair and maintenance of genomic integrity. In addition, PARP-1 has a role in several models of inflammation disease, where its absence or inactivation confers protection. The aim of t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1526570/ https://ncbi.nlm.nih.gov/pubmed/16356201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1865 |
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