Isotype-Restricted Corepressor Recruitment: a Constitutively Closed Helix 12 Conformation in Retinoic Acid Receptors β and γ Interferes with Corepressor Recruitment and Prevents Transcriptional Repression

Retinoic acid receptors (RARs) are ligand-regulated transcription factors that play multiple roles in vertebrate development and differentiation. RARs as a class are capable of both repressing and activating target gene expression. Transcriptional repression is mediated through the recruitment of co...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Farboud, Behnom, Hauksdottir, Herborg, Wu, Yun, Privalsky, Martin L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12665583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.8.2844-2858.2003
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