Isotype-Restricted Corepressor Recruitment: a Constitutively Closed Helix 12 Conformation in Retinoic Acid Receptors β and γ Interferes with Corepressor Recruitment and Prevents Transcriptional Repression

Retinoic acid receptors (RARs) are ligand-regulated transcription factors that play multiple roles in vertebrate development and differentiation. RARs as a class are capable of both repressing and activating target gene expression. Transcriptional repression is mediated through the recruitment of co...

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Bibliographische Detailangaben
Hauptverfasser: Farboud, Behnom, Hauksdottir, Herborg, Wu, Yun, Privalsky, Martin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Transcriptional Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152560/
https://ncbi.nlm.nih.gov/pubmed/12665583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.8.2844-2858.2003
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